High glucose macrophage

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August undefined, 2024

WebNational Center for Biotechnology Information Web1 de dez. de 2008 · Increased glucose is described to be involved in alterations of macrophages responses to lipopolysaccharide (LPS) in diabetic animal models, …

Hyperglycemia modulates M1/M2 macrophage polarization via

Web20 de ago. de 2024 · Specifically, hyperglycemia is recognized to increase bone marrow (BM) hematopoiesis, and thereby levels of monocytes and neutrophils that readily enter … Web14 de mar. de 2014 · Glucose is a critical component in the proinflammatory response of macrophages (MΦs). However, the contribution of glucose transporters (GLUTs) and the mechanisms regulating subsequent glucose metabolism in the inflammatory response are not well understood. orchid\u0027s new year\u0027s vacation

TAB1 regulates glycolysis and activation of macrophages in …

Web1 de dez. de 2008 · Increased glucose is described to be involved in alterations of macrophages responses to lipopolysaccharide (LPS) in diabetic animal models, including interleukin-12 expression [5], upregulation of cyclooxygenase-II, leading to increased prostaglandin-E 2 [6] and TNF-α production [7]. Web7 de set. de 2024 · We utilized an in vitro approach to determine the effects of high glucose on macrophage phenotype. Materials and methods: We exposed human THP-1 … Web11 de jul. de 2024 · The effect of long-term high glucose on macrophage glucose metabolism and mitochondrial oxygen consumption Immune cells’ function is … ir thermal sensor in laptop

Lean adipose tissue macrophage derived exosome confers …

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Web29 de jun. de 2024 · Here we show that LPS stimulation of RAW264.7 macrophage cells cultured in high glucose medium leads to pyroptosis, which can be suppressed by a … Web20 de jan. de 2024 · As shown in Figure 1A, macrophage-derived exosomal MALAT1 significantly increased from 12.5 mM to 50 mM of glucose concentration, and 25 mM high glucose had the maximal effect. Therefore, 25 mM high glucose was … orchidaceae family characteristicsWebHigh glucose contributes to the polarization of peritoneal macrophages to the M2 phenotype in vivo and in vitro. Glucose is the primary osmotic medium used in most … orchidamos

"WebRegardless their exact mode of action, our findings uncovered that exosomes produced by macrophages exposed to high glucose concentrations and those isolated from the plasma of diabetic mice and human subjects carry increased levels of select microRNA including miR-486-5p that is associated with dysfunctional hematopoiesis and macrophage … " - High glucose macrophage

High glucose macrophage

High glucose induces a priming effect in macrophages and …

Web1640 containing either 5.5 mM or 25 mM glucose, and incubated for 24 h. In some experiments, medium con-taining 5.5 mM glucose and 19.5 mM mannitol was used as an osmotic control. Protein microarray analyses THP-1 cells (5 x 10 5) incubated either with 5.5 mM or 25 mM glucose without FBS were stimulated with 1 ng/ml Web22 de jun. de 2010 · It is known that high glucose can induce cardiomyocyte apoptosis and that macrophage migration inhibitory factor (MIF) may be involved in the development of diabetes. ... High glucose (HG)-induced activation of caspase 3 is reduced by pretreatment of AC16 human cardiomyocytes with 2.5 μmol/L SP600125 ...

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Web12 de abr. de 2024 · Chronic non-healing wounds, a prevalent complication of diabetes, are associated with increased mortality in diabetic patients. Excessive accumulation of M1 macrophages in diabetic wounds promotes inflammation and results in dysregulated tissue repair. Adipose tissue macrophages (ATMs) derived from healthy lean donors have the …

Web22 de jun. de 2010 · It is known that high glucose can induce cardiomyocyte apoptosis and that macrophage migration inhibitory factor (MIF) may be involved in the development of … Web29 de out. de 2024 · The decrease in ETV5 expression resulted in macrophage ... EGFR tyrosine kinase inhibitor (PD153035) improves glucose tolerance and insulin action in high-fat diet-fed mice. Diabetes ...

WebmiR-210 in Exosomes Derived from Macrophages under High Glucose Promotes Mouse Diabetic Obesity Pathogenesis by Suppressing NDUFA4 Expression Feng Tian, 1 Ping Tang, 1Zhilian Sun, 1Ruifen Zhang, 1Danhua Zhu, 1Junying He, 1Jixing Liao, 1Qinghua Wan, 1and Jie Shen 2 Academic Editor: Janet H. Southerland Received 02 … WebThe overnutrition condition such as hyperglycaemia induces macrophage infiltration especially the inflammatory macrophages. The aim of this study was to analyse the …

WebThis study was, therefore, to investigate the mechanism by high glucose stimuli. Methods: In this study, Raw264.7 (murine macrophage cell line) cells were cultured and stimulated …

WebWe used C57BLKS/6J Lepdb/db mice and a high glucose (HG)-induced bone marrow-derived macrophage (BMDM) polarization system to investigate the potentially protective effects of HPS on DN. Our results showed that HPS markedly reduced diabetes-induced albuminuria and glomerular mesangial matrix expansion, accompanied with a significant … ir thermometer definitionWeb1 de abr. de 2024 · MAIT cell inhibition reduces inflammatory and fibrogenic genes in human PCLS. We evaluated the consequences of MAIT cell inhibition on liver fibrogenesis in human liver samples, using ex vivo PCLS ... ir thermometer autozoneWeb13 de jul. de 2024 · In macrophages, high extracellular glucose promoted proinflammatory gene expression and proatherogenic functional characteristics through glycolysis-dependent mechanisms. Bone marrow–derived macrophages from diabetic mice retained these characteristics, even when cultured in physiological glucose, indicating hyperglycemia … ir thermometer amazonWeb1 de jul. de 2024 · In this article, we try to investigate whether high glucose (HG)-treated macrophages-derived exosomes could activate macrophages and induce inflammatory responses in vivo and in vitro. We incubated the exosomes from high glucose-treated Raw264.7 cells (HG-Exo) and Raw264.7 cells for 24 h. ir thermometer 3d printer bed temperatureWeb25 de mar. de 2015 · The present study investigates the effect of 1,25-dihydroxyvitamin D 3 on macrophage activation state and its underlying mechanism in RAW264.7 cells. We find that, under high glucose conditions, RAW264.7 macrophages tend to switch to the M1 phenotype, expressing higher iNOS and proinflammatory cytokines, including TNF α and … ir thermometer candyWebWe evaluated the effect of high glucose conditions on the inflammatory profile and the autophagy pathway in Bone-Marrow Derived Macrophages ... Xu H, Chen M. Sustained … ir thermometer boardWeb7 de set. de 2024 · Without any stimulation, macrophages cultured in high glucose conditions (15 mM, 522.6 ± 232.9 pg/mL) displayed a higher concentration of TNF-α … orchidantha chinensis