Solubility of benzocaine in water
Webbenzocaine* 0.6 0.9 0.4 tetracaine* 0.7 0.9 0.6 lidocaine 0.9 1.0 0.9 cocaine 1.0 1.0 1.0 3.4. GAS CHROMATOGRAPHY Method COC-GCS1 Instrument: Gas chromatograph operated in split mode with FID Column: 5% phenyl/95% methyl silicone 12 m x 0.2 mm x 0.33 µm film thickness Carrier gas: Helium at 1.0 mL/min Temperatures: Injector: 270°C Benzocaine is the ethyl ester of p-aminobenzoic acid (PABA). It can be prepared from PABA and ethanol by Fischer esterification or via the reduction of ethyl p-nitrobenzoate. Benzocaine is sparingly soluble in water; it is more soluble in dilute acids and very soluble in ethanol, chloroform, and ethyl ether. The melting point of benzocaine is 88–92 °C, and the boiling point is about 310 °C. The density of benzocaine is 1.17 g/cm .
Solubility of benzocaine in water
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WebBenzocaine has limited solubility in water, but its conjugate acid is completely soluble in water. Draw the structure of the product formed from the reaction of benzocaine with hydrochloric acid. Click in the checkered box to open the structure drawing tool box. WebApr 3, 2024 · Benzocaine is a colorless trapezial crystal. Its melting point is 92℃ (88-90℃), boiling point is 183-184°C (1.87kPa). 1g of this drug is soluble in about 2500ml water, 5ml …
WebJohn E. Tetzlaff, in Pharmacology and Therapeutics, 2009 Benzocaine (Fig. 59-6).Benzocaine is a benzoic acid derivative that as a secondary amine, is the only … WebThe equilibrium solubility of benzocaine (BZC) in several {methanol (1) + water (2)} mixtures at 298.15 K was determined. Solubility values are expressed in mole fraction and molarity …
WebJan 9, 2011 · Benzocaine is an effective general anesthetic for fish. Its solubility was determined in waters of various hardness and pH and over a range of temperatures (from 5 to 30°C). Variations in water hardness and pH did not appreciably affect the solubility of Benzocaine, whereas increases in temperature increased solubility from 409 mg/L (at 5°C … WebExpert Answer. 100% (4 ratings) Transcribed image text: Benzocaine has limited solubility in water, but its conjugate acid is completely soluble in water. Draw the structure of the …
WebNov 15, 2004 · The solubility curves as a function of dioxane ratio showed a maximum at 90% dioxane at all temperatures. Above … The solubilities of benzocaine and salicylic acid … how to remove mold stainWebWhat is the solubility of benzocaine in water g ml? Benzocaine is a surface anesthetic that reversibly inactivates voltage-dependent sodium channels. Solubility : Soluble in water … noris record 200WebBenzocaine. Molecular Formula CHNO. Average mass 165.189 Da. Monoisotopic mass 165.078979 Da. ChemSpider ID 13854242. how to remove molds overnightWebUnanswered Benzocaine is insoluble in water at all temperatures, but does show a slight increase in solubility at higher temperatures. Which PEC diagram best represents the mixed (M) and unmixed (UM) state of benzocaine in water? B с A UM E. M E. M UM UM M # of configurations # of configurations # of configurations D E F UM M E. UM how to remove mold stains from vinylWebOct 4, 2005 · Benzocaine (BZC) is a local anesthetic whose low water-solubility limits its application to topical formulations. The present work focuses on the characterization of inclusion complexes of BZC in beta-cyclodextrin (beta-CD). Differential scanning calorimetry and electron microscopy gave evidences of the formation and the morphology of the … how to remove moldy caulk from bathtubWebFeb 2, 2024 · The present invention provides formulations of nanostructured gels for increased drug loading and adhesion. A wide range of drugs, particularly highly loaded with amine-containing compounds such as local anesthetics, which are known to be difficult to encapsulate (e.g., about 5% wt/wt drug/total gel weight and about 50% wt/wt drug/total … how to remove mold spores in airWebDec 1, 2002 · Benzocaine is sparingly soluble in water or an aqueous environment (solubility approx. 9.35 mmol/L at 37°C in aqueous media, with pH 7.4 and ionic strength 0.15 mol/L [16]), but its good ... how to remove mold stains from rubber